BMS 695735
BMS 695735 (compound 10) is an inhibitor of IGF-1R with an IC50 value of 0.034 μM. BMS 695735 has anti-tumor activity.
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- No. CAS: 1054315-48-8
- Fòrmula: C26H31ClFN7O
- Peso molecular:512.02
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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- Referencias
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Help & FAQs
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HY-10191
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Linsitinib (Standard)IGF-1R/Insulin Receptor Inhibitor -
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NBI-31772 (Standard)IGFBP Inhibitor
Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U-937 | IC50 |
4 μM
Compound: 10, BMS-695735
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Inhibition of human PDE4 in U937 cells
Inhibition of human PDE4 in U937 cells
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[PMID: 18763755] |
Chemical Information
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No. CAS 1054315-48-8
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Peso molecular 512.02
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Fòrmula C26H31ClFN7O
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SMILES
O=C1C(C2=NC3=C(C)C=C(C4CCN(CCCF)CC4)C=C3N2)=C(NCCN5N=CC(Cl)=C5)C=CN1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Discovery and Evaluation of 4-(2-(4-chloro-1H-pyrazol-1-yl)ethylamino)-3-(6-(1-(3-fluoropropyl)piperidin-4-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (BMS-695735), an Orally Efficacious Inhibitor of Insulin-like Growth Factor-1 Receptor Kinase with Broad Spectrum in Vivo Antitumor Activity J. Med. Chem., 2008, 51 (19), pp 5897-5900 [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMS 695735 Related Classifications
HY-14357 Related Classifications
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