Bocunebart
Based on 1 Customer Validation
Bocunebart is a humanized monoclonal antibody targeting human adenylate cyclase-activating polypeptide (ADCYAP1). Bocunebart exerts anti-inflammatory activity by specifically binding to ADCYAP1 and inhibiting related inflammatory signaling pathways. Bocunebart is promising for research of inflammation-related diseases.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 99.25%
- No. CAS: 2984605-64-1
- Peso molecular:143.474 kDa
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Almacenamiento:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
ADCYAP1
In Vitro
Bocunebart is a humanized monoclonal antibody targeting human adenylate cyclase-activating polypeptide[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Ensayo clínico
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | 2011-05 | PHASE1 |
Gene ID
Accession
Conjugated
Unconjugated
Reconstitution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-kappa
Aplicación
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized PACAP-1-38 can bind Bocunebart. The EC50 for this effect is 139.3 ng/mL.
Chemical Information
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No. CAS 2984605-64-1
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Appearance Liquid
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Peso molecular 143.474 kDa
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Color Colorless to light yellow
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SMILES
[Bocunebart]
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Synonyms
ALD1910; LU AG-09222
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Envío
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (255 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)