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Referencia número: HY-161897

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CENP-E-IN-2

CENP-E-IN-2 (compound 3) is a photoswitchable CENP-E inhibitor, with the pIC₅₀ of 6.82 without light illumination and 5.85 with 365 nm light illumination. CENP-E-IN-2 has antitumor activity.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₂₇H₃₃ClN₆O₄
Peso molecular:541.04

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

CENP-E-IN-2 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

IC₅₀ & Target

CENP-E

Ver todos los productos específicos de isoformas Kinesin :

Chemical Information

Peso molecular 541.04
Fòrmula C₂₇H₃₃ClN₆O₄
SMILES

ClC1=C(OC(C)C)C=CC(C(N[C@H](C(NC)=O)CC2=CC=C(/N=N/C3=C(C)N(CCO)N=C3C)C=C2)=O)=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Kazuya Matsuo, et al. A chemical platform for the efficient screening of arylazopyrazole-based photoswitchable CENP-E inhibitors using mild cyclization reactions. Bioorg Med Chem Lett. 2024 Jul 17:111:129892. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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- IC₅₀ & Target
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CENP-E-IN-2

Ver todos los productos específicos de isoformas Kinesin

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

CENP-E-IN-2 Related Classifications

HY-161897 Related Classifications