COTC
COTC is a bacterial metabolite with anticancer activity that is found in S. griseosporeus. COTC inhibits glyoxalase in the presence of glutathione (GSH). COTC also inhibits the proliferation of HeLa cells (IC50 = 18 µg/mL), as well as reduces tumor growth and improves survival in an Ehrlich murine spontaneous adenocarcinoma model.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 57449-30-6
- Fòrmula: C11H14O6
- Peso molecular:242.23
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Chemical Information
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No. CAS 57449-30-6
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Peso molecular 242.23
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Fòrmula C11H14O6
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SMILES
C/C=C/C(OCC1=C[C@@H](O)[C@@H](O)[C@@H](O)C1=O)=O
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Structure Classification
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Initial Source
Streptomyces griseosporeus
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)