CSLP37
CSLP37 is a selective RIPK2 inhibitor with an IC50 of 16.3 nM. CSLP37 shows no inhibitory activity against RIPK1 and RIPK3. CSLP37 displays potent suppression of cellular NOD1 and NOD2 responses.
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- No. CAS: 2244984-64-1
- Fòrmula: C25H30FN5O3S
- Peso molecular:499.60
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
[1]|
RIPK2 16.3 nM (IC50) |
Chemical Information
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No. CAS 2244984-64-1
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Peso molecular 499.60
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Fòrmula C25H30FN5O3S
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SMILES
CCCS(=O)(NC1=CC(C2=CC(C3=CC=C(N4CCNCC4)C=C3)=CN=C2N)=CC(F)=C1OC)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CSLP37 Related Classifications
HY-123924 Related Classifications
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