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Referencia número: HY-115836

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DDPO

DDPO is an inhibitor for dihydrofolate reductase (DHFR) with an IC₅₀ of 0.035 µM. DDPO inhibits the cell growth of cancer cell L1210 and WI-L2with IC₅₀ of 5 and 0.28 µM.

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No. CAS: 118675-83-5
Fòrmula: C₂₁H₂₄N₆O₄
Peso molecular:424.45

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

DDPO Chemical Structure

No. CAS: 118675-83-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

DDPO is an inhibitor for dihydrofolate reductase (DHFR) with an IC₅₀ of 0.035 µM. DDPO inhibits the cell growth of cancer cell L1210 and WI-L2with IC₅₀ of 5 and 0.28 µM^[1].

Chemical Information

No. CAS 118675-83-5
Peso molecular 424.45
Fòrmula C₂₁H₂₄N₆O₄
SMILES

O=C1C2=CC(CNC3=CC=C(C=C3)C(N[C@H](C(O)=O)CCCN)=O)=CC=C2NC(N)=N1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Rosowsky A, et al., Synthesis and in vitro biological activity of new deaza analogues of folic acid, aminopterin, and methotrexate with an L-ornithine side chain.

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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