DHPCC-9
DHPCC-9 acts as an inhibitor of Pim kinase.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1192248-37-5
- Fòrmula: C15H10N2O
- Peso molecular:234.25
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
Descripciòn
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| DU-145 | IC50 |
26 μM
Compound: 9
|
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin dye reduction assay
|
[PMID: 19788246] |
| DU-145 | IC50 |
26 μM
Compound: A
|
Cytotoxicity against human DU145 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human DU145 cells after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| DU-145 | IC50 |
26 μM
Compound: A
|
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin reduction test
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin reduction test
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[PMID: 22982527] |
| Fibroblast | IC50 |
21 μM
Compound: 9
|
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin dye reduction assay
|
[PMID: 19788246] |
| Fibroblast | IC50 |
21 μM
Compound: A
|
Cytotoxicity against human fibroblasts after 48 hrs by resazurin reduction test
Cytotoxicity against human fibroblasts after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| Fibroblast | IC50 |
21 μM
Compound: A
|
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
| PA-1 | IC50 |
4.5 μM
Compound: 9
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Antiproliferative activity against human PA1 cells after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin dye reduction assay
|
[PMID: 19788246] |
| PA-1 | IC50 |
4.5 μM
Compound: A
|
Cytotoxicity against human PA1 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human PA1 cells after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| PA-1 | IC50 |
4.5 μM
Compound: A
|
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
| PC-3 | IC50 |
9.5 μM
Compound: 9
|
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin dye reduction assay
|
[PMID: 19788246] |
| PC-3 | IC50 |
9.5 μM
Compound: A
|
Cytotoxicity against human PC3 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human PC3 cells after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| PC-3 | IC50 |
9.5 μM
Compound: A
|
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin reduction test
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
Chemical Information
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No. CAS 1192248-37-5
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Peso molecular 234.25
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Fòrmula C15H10N2O
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SMILES
O=CC1=CNC2=C1C=CC3=C2NC4=C3C=CC=C4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DHPCC-9 Related Classifications
HY-115837 Related Classifications
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