DN-108
DN-108, a thiazolidinedione derivative, is an orally active peroxisome proliferator-activated receptor γ (PPARγ) agonist with antidiabetic effects. DN-108 improves hyperglycemia, hypertriglyceridemia and hyperinsulinemia in diabetic mouse models. DN-108 enhances tissue glucose uptake (e.g., increasing 2-deoxyglucose uptake in L6 muscle cells) and inhibits fatty acid synthase activity. DN-108 is promising for research of type 2 diabetes.
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- No. CAS: 195604-21-8
- Fòrmula: C20H18N2O3S
- Peso molecular:366.43
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
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PPARγ |
Chemical Information
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No. CAS 195604-21-8
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Peso molecular 366.43
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Fòrmula C20H18N2O3S
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SMILES
O=C1SC(CC2=CC=C(NC(C3(CC3)C4=CC=CC=C4)=O)C=C2)C(N1)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DN-108 Related Classifications
HY-171793 Related Classifications
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