DS42450411
DS42450411 is an orally active hepcidin production inhibitor with an IC50 of 32 nM. DS42450411 in an acute inflammatory mouse model induced by IL-6, DS42450411 significantly reduces serum hepcidin levels. DS42450411 can be used for studying iron homeostasis.
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- No. CAS: 2247168-13-2
- Fòrmula: C22H28N4
- Peso molecular:348.48
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
0.032 μM
Compound: 34; DS42450411
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Inhibition of BMP6-stimulated hepcidin production in human HepG2 cells
Inhibition of BMP6-stimulated hepcidin production in human HepG2 cells
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[PMID: 30217414] |
Chemical Information
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No. CAS 2247168-13-2
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Peso molecular 348.48
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Fòrmula C22H28N4
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SMILES
NC1=C2C(C)(C)CC3=CC(C([C@H]4CC[C@H](N)CC4)=C)=CC=C3C2=NC=N1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DS42450411 Related Classifications
HY-125288 Related Classifications
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