DSP-0390
DSP-0390 is an orally effective inhibitor of Emopamil-binding protein (EBP). DSP-0390 blocks the cholesterol de novo synthesis pathway in tumor cells by inhibiting EBP, and demonstrates significant anti-tumor activity in an orthotopic xenograft model of glioblastoma (GBM). DSP-0390 can be used for the study of recurrent high-grade gliomas.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2376765-57-8
- Fòrmula: C23H30ClN3O2
- Peso molecular:415.96
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
-
No. CAS 2376765-57-8
-
Peso molecular 415.96
-
Fòrmula C23H30ClN3O2
-
SMILES
CC1([C@]2([H])CC3(CCN(CC3)CCN4C=CN=C4)CO[C@@]2([H])C5=CC=C(Cl)C=C5O1)C
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DSP-0390 Related Classifications
HY-157828 Related Classifications
Powered by Bioz