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Referencia número: HY-105128

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Epostane

(Synonyms: WIN 32729)

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Epostane (WIN 32729) is an orally active inhibitor for 3β-hydroxysteroid dehydrogenase, with IC₅₀ of 1.45 nM. Epostane blocks ovulation and pregnancy in rats.

Para uso exclusivo en investigación. No vendemos a pacientes.

Pureza: 99.0%
No. CAS: 80471-63-2
Fòrmula: C₂₂H₃₁NO₃
Peso molecular:357.49

Almacenamiento:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Epostane Chemical Structure

No. CAS: 80471-63-2

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Actividad biológica
- Descripciòn
- In Vivo
Chemical Information
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Actividad biológica

Descripciòn

Epostane (WIN 32729) is an orally active inhibitor for 3β-hydroxysteroid dehydrogenase, with IC₅₀ of 1.45 nM. Epostane blocks ovulation and pregnancy in rats^[1].

Ver todos los productos específicos de isoformas 3β-HSD :

3β-HSD I

In Vivo

Epostane (0-200 mg/kg, p.o., single dose) inhibits ovulation in mature rats and gonadotropin-stimulated ovulation in immature rats, terminates pregnancy through lowering plasma progesterone levels^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Sprague Dawley rats model^[1]
Dosage:

0-200 mg/kg
Administration:

p.o., single dose
Result:

Terminated ovulation and pregnancy in rats, which was reversed by injections of progesterone.

Chemical Information

No. CAS 80471-63-2
Appearance Solid
Peso molecular 357.49
Fòrmula C₂₂H₃₁NO₃
Color White to off-white
SMILES

C[C@@]12[C@@]3(CC[C@]4([H])[C@]2([H])CC[C@]5([C@@]4([H])CC[C@@]5(O)C)C)[C@](O3)(C(O)=C(C1)C#N)C
Synonyms

WIN 32729
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (272 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Snyder BW, et al., Inhibition of ovulation in rats with epostane, an inhibitor of 3 beta-hydroxysteroid dehydrogenase. Proc Soc Exp Biol Med. 1984 Jul;176(3):238-42. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Epostane

Ver todos los productos específicos de isoformas 3β-HSD

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Epostane Related Classifications

HY-105128 Related Classifications