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Referencia número: HY-167866

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Ersentilide

Ersentilide, a benzamide derivative, is a is a β1-adrenoceptor antagonist and Ikr blocker. Ersentilide is effective in several intact animal models of arrhythmia.

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No. CAS: 125279-79-0
Fòrmula: C₂₁H₂₆N₄O₅S
Peso molecular:446.52

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Ersentilide Chemical Structure

No. CAS: 125279-79-0

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Ersentilide, a benzamide derivative, is a is a β1-adrenoceptor antagonist and Ikr blocker. Ersentilide is effective in several intact animal models of arrhythmia^[1]^[2].

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Chemical Information

No. CAS 125279-79-0
Peso molecular 446.52
Fòrmula C₂₁H₂₆N₄O₅S
SMILES

CS(NC(C=C1)=CC=C1OC[C@@H](O)CNCCOC2=CC=C(N3C=CN=C3)C=C2)(=O)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocolo

All Signal Pathway Related

Cardiac voltage-sensitive optical mapping
Cardiac voltage-sensitive optical mapping records changes in transmembrane potential from cardiac tissue by staining the preparation with a voltage-sensitive dye and imaging fluorescence changes during electrical activation; the resulting optical action potentials can be used to map activation time, action potential duration, conduction velocity, wavefront propagation, and arrhythmia dynamics. The optical signal represents a relative fluorescence change from a tissue volume rather than a single-cell intracellular recording, so spatial resolution, sampling rate, voltage resolution, optical magnification, light penetration, and motion control must be considered together when interpreting optical action potentials.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Adamson PB, et, al. Antifibrillatory efficacy of ersentilide, a novel beta-adrenergic and Ikr blocker, in conscious dogs with a healed myocardial infarction. Cardiovasc Res. 1998 Oct;40(1):56-63. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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