Flipper-TR 5
Flipper-TR 5 is a Flipper probe containing a terminal carboxylate for retention on the plasma membrane. Flipper-TR 5 selectively labels the cytoplasmic membrane, and exhibits excellent mechanical sensitivity, negligible cytotoxicity and controllable phototoxicity.
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- No. CAS: 2081888-04-0
- Fòrmula: C27H20N4O5S6
- Peso molecular:672.86
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
Flipper-TR 5 exhibits ground-state planarization-dependent fluorescence and spectral shifts in solution and lipid bilayer membranes, with increasing red shifts, fluorescence intensity, and vibrational finestructure in increasingly ordered membranes[1].
Flipper-TR 5 shows longer fluorescence lifetimes in more ordered Lo lipid bilayer membranes compared to Ld membranes in GUVs, with non-selective partitioning but phase-dependent fluorescence intensity[1].
Flipper-TR 5 reports on membrane tension and organization in living cells, with fluorescence lifetimes that shift in response to hyperosmotic stress in plasma membranes, ER, and Golgi apparatus, and baseline lifetime differences driven by membrane order[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2081888-04-0
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Peso molecular 672.86
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Fòrmula C27H20N4O5S6
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SMILES
CC1=C(C#N)SC(C2=C3C(C)=C(C4=C(C)C(SC5=C6SC(COCC7=CN(CC(O)=O)N=N7)=C5C)=C6S4)S2)=C1S3(=O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Flipper-TR 5 Related Classifications
HY-D2318 Related Classifications
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