Glenthmycin A
Glenthmycin A is a macrocyclic type II spiroketal polyketide antibacterial agent. Glenthmycin A inhibits the growth of Gram-positive pathogens. Glenthmycin A is applicable to the research of bacterial infections.
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- No. CAS: 3040055-59-9
- Fòrmula: C49H63NO13
- Peso molecular:874.04
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Glenthmycin A (Compound 1) (0.01-30 μM; 16-24 h) inhibits the growth of S. aureus ATCC 25923 (IC50 6.4 μM), E. faecalis (IC50 5.7 μM), MRSA ATCC 43300 (IC50 4.4 μM), MRSA ATCC 33591 (IC50 1.9 μM), and VRE (IC50 5.2 μM)[1].
Glenthmycin A (30 μM; 48 h) does not exhibit significant cytotoxicity against human colorectal carcinoma (SW620) or human lung carcinoma (NCI-H460) cells, with IC50 > 30 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 3040055-59-9
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Peso molecular 874.04
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Fòrmula C49H63NO13
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SMILES
OC=1[C@@]23[C@@](C=C(C(O)=O)[C@H](C)C2)(/C=C(\C)/CC/C=C(\C)/[C@]4([C@@](C)(C(=O)C1C(=O)O3)[C@]5([C@@]([C@@H](O[C@H]6[C@H](O)[C@](C)(O)[C@H](NC(=O)C7=C(C)C=C(OC)C=C7O)[C@@H](C)O6)CC[C@@H]5C)(C=C4C)[H])[H])[H])[H]
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Structure Classification
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Initial Source
Streptomyces sp.
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glenthmycin A Related Classifications
HY-N19212 Related Classifications
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