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United States

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Referencia número: HY-P10321

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HBP08

HBP08 is a selective inhibitor of CXCL12/HMGB1 interaction. HBP08 has a high affinity for HMGB1 (K_d=0.8 μM). HBP08 inhibits CXCL12-mediated cell migration.

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No. CAS: 2490442-13-0
Fòrmula: C₆₀H₇₇N₁₇O₁₄
Peso molecular:1260.36

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

HBP08 Chemical Structure

No. CAS: 2490442-13-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

HBP08 is a selective inhibitor of CXCL12/HMGB1 interaction. HBP08 has a high affinity for HMGB1 (K_d=0.8 μM). HBP08 inhibits CXCL12-mediated cell migration^[1].

Ver todos los productos específicos de isoformas CXCR :

Chemical Information

No. CAS 2490442-13-0
Peso molecular 1260.36
Fòrmula C₆₀H₇₇N₁₇O₁₄
Sequence

Gly-Tyr-His-Tyr-Glu-Arg-Trp-Ile-His
Sequence Shortening

GYHYERWIH
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (257 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Sgrignani J, et al. Systematic Development of Peptide Inhibitors Targeting the CXCL12/HMGB1 Interaction. J Med Chem. 2021 Sep 23;64(18):13439-13450. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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HBP08

Ver todos los productos específicos de isoformas CXCR

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

HBP08 Related Classifications

HY-P10321 Related Classifications