IPPD-Q
Based on 1 publication(s) in Google Scholar
IPPD-Q is a p-phenylenediamine quinone and also Environmental pollutant. IPPD-Q can be present in tires, fine particulate matter and urban water bodies. IPPD-Q increases the activities of antioxidant enzymes (SOD, CAT), alters photosynthesis and energy metabolism pathways, and changes gene expression and metabolic profiles. IPPD-Q exhibits phytotoxic effects. IPPD-Q shows acute toxicity to zebrafish embryos and reduces their survival rate.
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- Pureza: 97.38%
- No. CAS: 68054-73-9
- Fòrmula: C15H16N2O2
- Peso molecular:256.30
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) IPPD-Q
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Actividad biológica
Descripciòn
In Vitro
IPPD-Q (0.1-1000 μg/L; 21 days) exposure induces concentration-dependent effects on wheat seedlings, reducing shoot length at high concentrations (100, 1000 μg/L), increasing fresh weight at low concentrations (0.1, 1, 10 μg/L), altering osmoprotectant levels, and modulating the uptake of multiple nutrient elements[2].
IPPD-Q (0.1-1000 μg/L; 21 days) exposure enhances photosynthetic pigment levels and stomatal conductance in wheat seedlings, while inducing oxidative stress via increased antioxidant enzyme (SOD, POD, CAT) activities and MDA content, with concentration-dependent effects on photosynthetic gas exchange parameters[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Danio rerio larvae[3]
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Dosage:10 μg/L
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Administration:aqueous exposure; continuous; 96 hours
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Result:Reduced zebrafish embryo survival rate to 73.3% (vs 95.3% in blank control).
Reached a minimum survival rate of 20.7% at 20 minutes of chlorination reaction time, before recovering to 58.7% at 360 minutes.
Reached a minimum survival rate of 40.7% at 30 minutes of chloramination reaction time.
Caused significantly sparser locomotor trajectories in surviving embryos exposed to chlorination transformation products compared to chloramination transformation products or parent IPPD-Q.
Had a predicted 96 h LC50 of 26.174 mg/L, while TP-290-1 (mono-Cl substitution at C2) had a predicted 96 h LC50 of 19.107 mg/L.
Chemical Information
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No. CAS 68054-73-9
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Appearance Solid
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Peso molecular 256.30
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Fòrmula C15H16N2O2
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Color Brown to reddish brown
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SMILES
O=C1C(NC(C)C)=CC(C(NC2=CC=CC=C2)=C1)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Environ Pollut
2026 Jul 1:400:128295. PMID: 42105897
Solvente y solubilidad
In Vitro:
DMSO : 25 mg/mL (97.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (276 KB)
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SDS (537 KB)
- English - EN (537 KB)
- Français - FR (537 KB)
- Deutsch - DE (537 KB)
- Norwegian - NO (537 KB)
- Español - ES (537 KB)
- Swedish - SV (537 KB)
- Italian - IT (537 KB)
- Korean - KR (537 KB)
- Portuguese - PT (537 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Wang W, et al. Beyond Substituted -Phenylenediamine Antioxidants: Prevalence of Their Quinone Derivatives in PM. Environmental science & technology. 2022 Aug 02;56(15):10629-10637. [Content Brief]
[3]. Chen H, et al. Mechanistic insights into the transformation and toxicity evolution of IPPD-Q during chlorination and chloramination in drinking water. Water research. 2026 Jan 15;289(Pt A):124884. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9017 mL | 19.5084 mL | 39.0168 mL | 97.5419 mL |
| 5 mM | 0.7803 mL | 3.9017 mL | 7.8034 mL | 19.5084 mL | |
| 10 mM | 0.3902 mL | 1.9508 mL | 3.9017 mL | 9.7542 mL | |
| 15 mM | 0.2601 mL | 1.3006 mL | 2.6011 mL | 6.5028 mL | |
| 20 mM | 0.1951 mL | 0.9754 mL | 1.9508 mL | 4.8771 mL | |
| 25 mM | 0.1561 mL | 0.7803 mL | 1.5607 mL | 3.9017 mL | |
| 30 mM | 0.1301 mL | 0.6503 mL | 1.3006 mL | 3.2514 mL | |
| 40 mM | 0.0975 mL | 0.4877 mL | 0.9754 mL | 2.4385 mL | |
| 50 mM | 0.0780 mL | 0.3902 mL | 0.7803 mL | 1.9508 mL | |
| 60 mM | 0.0650 mL | 0.3251 mL | 0.6503 mL | 1.6257 mL | |
| 80 mM | 0.0488 mL | 0.2439 mL | 0.4877 mL | 1.2193 mL |
IPPD-Q Related Classifications
HY-W754777 Related Classifications
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