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Referencia número: HY-159985

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Jun13728

Jun13728 is a potent and covalent SARS-CoV-2 papain-like protease inhibitor, with an IC₅₀ of 0.1 μM. Jun13728 can be used for SARS-CoV-2 antiviral research.

Para uso exclusivo en investigación. No vendemos a pacientes.

Fòrmula: C₃₄H₃₆F₂N₈O₄
Peso molecular:658.70

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Jun13728 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Jun13728 is a potent and covalent SARS-CoV-2 papain-like protease inhibitor, with an IC₅₀ of 0.1 μM. Jun13728 can be used for SARS-CoV-2 antiviral research^[1].

Chemical Information

Peso molecular 658.70
Fòrmula C₃₄H₃₆F₂N₈O₄
SMILES

O=C(N[C@@H](C1=CC(C2=CN(N=C2)C)=CC(C3=NN(C=C3)CC)=C1)C)C4=CC=CC=C4CCC(NNC(/C=C/C(N5CC(F)(C5)F)=O)=O)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Tan B, et, al. Structure-Based Design of Covalent SARS-CoV-2 Papain-like Protease Inhibitors. J Med Chem. 2024 Nov 28;67(22):20399-20420. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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