L742791
L742791 is a β3-AR agonist. L742791 elicits lipolytic response in isolated nonhuman primate adipocytes.
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- No. CAS: 159182-18-0
- Fòrmula: C23H25IN2O5S
- Peso molecular:568.42
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Ver todos los productos específicos de isoformas Adrenergic Receptor
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
Beta-3 adrenergic receptor |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
120 nM
Compound: 40
|
Binding affinity against cloned human beta-2 adrenergic receptor from CHO cells using [125I]iodocyanopindolol as the radioligand
Binding affinity against cloned human beta-2 adrenergic receptor from CHO cells using [125I]iodocyanopindolol as the radioligand
|
[PMID: 9871716] |
| CHO | IC50 |
170 nM
Compound: 40
|
Tested for binding affinity against cloned human beta-1 adrenergic receptor from CHO cells using [125I]iodocyanopindolol as the radioligand
Tested for binding affinity against cloned human beta-1 adrenergic receptor from CHO cells using [125I]iodocyanopindolol as the radioligand
|
[PMID: 9871716] |
Chemical Information
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No. CAS 159182-18-0
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Peso molecular 568.42
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Fòrmula C23H25IN2O5S
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SMILES
O=S(C1=CC=C(C=C1)I)(NC2=CC=C(C=C2)CCNC[C@@H](COC3=CC=C(C=C3)O)O)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)