LY550410
LY550410 is a small-molecule ATP-competitive inhibitor against type I TGF-β receptor kinase, which contains heteroaryl rings for potent binding to the kinase-domain active site. LY550410 modulates TGF-β signalling, thereby regulates gene expression and ultimately cell growth. LY550410 is promising for research of cancers.
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- No. CAS: 737791-20-7
- Fòrmula: C20H16N4
- Peso molecular:312.37
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
51 μM
Compound: 3
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Inhibitory activity tested in NIH 3T3 cells
Inhibitory activity tested in NIH 3T3 cells
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[PMID: 15177480] |
Chemical Information
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No. CAS 737791-20-7
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Peso molecular 312.37
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Fòrmula C20H16N4
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SMILES
C12=C(C3=C4N(CCC4)N=C3C5=CC=CC=N5)C=CN=C1C=CC=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
LY550410 Related Classifications
HY-W684904 Related Classifications
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