m-PEG8-DBCO
m-PEG8-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG8-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Fòrmula: C36H50N2O10
- Peso molecular:670.79
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Peso molecular 670.79
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Fòrmula C36H50N2O10
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SMILES
O=C(CCC(NCCOCCOCCOCCOCCOCCOCCOCCOC)=O)N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)