ML301
ML301 is a small molecule G-protein agonist. ML301 can be inhibited by SR142948A with an IC50 of around 63 nM. ML301 fully competes for 125I-NT binding.
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- No. CAS: 1531633-84-7
- Fòrmula: C27H27ClN4O5
- Peso molecular:522.98
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
0.298 μM
Compound: 1, ML301
|
Agonist activity at NTR1 (unknown origin) expressed in CHO cells assessed as Ca2+ mobilization by Fluo-4 NW dye-based fluorescence assay
Agonist activity at NTR1 (unknown origin) expressed in CHO cells assessed as Ca2+ mobilization by Fluo-4 NW dye-based fluorescence assay
|
[PMID: 24332089] |
Chemical Information
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No. CAS 1531633-84-7
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Peso molecular 522.98
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Fòrmula C27H27ClN4O5
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SMILES
CC(C)C[C@@H](C(O)=O)NC(C1=CN(C2=CC=NC3=C2C=CC(Cl)=C3)C(C4=C(C=CC=C4OC)OC)=N1)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)