NRX-252114 (Standard)
NRX-252114 (Standard) is the analytical standard of NRX-252114 (HY-111836). This product is intended for research and analytical applications. NRX-252114 is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-252114 enhances the binding of pSer33/S37A β-catenin peptide for β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. NRX-252114 induces mutant β-catenin degradation.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2763260-39-3
- Fòrmula: C22H12Cl2F3N3O2S
- Peso molecular:510.31
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
No. CAS 2763260-39-3
-
Peso molecular 510.31
-
Fòrmula C22H12Cl2F3N3O2S
-
SMILES
N#CC1=CC=CC2=C1CN(C(=O)C=3C(=O)NC(=CC3SC=4C(Cl)=CC=CC4Cl)C(F)(F)F)C2
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)