NRX-252114 (Standard)

NRX-252114 (Standard) is the analytical standard of NRX-252114 (HY-111836). This product is intended for research and analytical applications. NRX-252114 is a potent enhancer of the interaction between β-catenin, and its cognate E3 ligase, SCFβ-TrCP. NRX-252114 enhances the binding of pSer33/S37A β-catenin peptide for β-TrCP with an EC50 of 6.5 nM and a Kd of 0.4 nM. NRX-252114 induces mutant β-catenin degradation.

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  • No. CAS: 2763260-39-3
  • Fòrmula: C22H12Cl2F3N3O2S
  • Peso molecular:510.31
  • Almacenamiento:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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