country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Referencia número: HY-180321

Copy Link Print Information

OAT-1441

OAT-1441 is a selective hAMCase inhibitor with oral activity (IC₅₀ = 7 nM). OAT-1441 can be used to study the physiological functions of hAMC enzymes.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 2088453-79-4
Fòrmula: C₂₃H₂₇ClN₆O
Peso molecular:438.96

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

OAT-1441 Chemical Structure

No. CAS: 2088453-79-4

Tamaño

Precio

Stock

Cantidad

Amount: USD 0.00

* Seleccione Cantidad antes de agregar artículos.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

OAT-1441 is a selective hAMCase inhibitor with oral activity (IC₅₀ = 7 nM). OAT-1441 can be used to study the physiological functions of hAMC enzymes^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
CHO-K1	IC₅₀	23000 nM Compound: 11; OAT-1441	Inhibition of human ERG expressed in CHO-K1 cells by automated Qpatch-clamp assay Inhibition of human ERG expressed in CHO-K1 cells by automated Qpatch-clamp assay	[PMID: 32551005]

Chemical Information

No. CAS 2088453-79-4
Peso molecular 438.96
Fòrmula C₂₃H₂₇ClN₆O
SMILES

C([C@@H]1N(CC=2C(OC1)=CC=CC2)C3CCN(CC3)C=4NC(N)=NN4)C5=CC=C(Cl)C=C5
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Andryianau G,et al. Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase. ACS Med Chem Lett. 2020 Apr 24;11(6):1228-1235. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtener un presupuesto En stock

Other size

Obtener un presupuesto