PF-4178903
PF-4178903 (INCB10820) is an orally active, potent dual CCR2 and CCR5 antagonist with IC50 values of 3 nM and 5.3 nM, respectively. PF-4178903 is promising for research of chronic inflammatory and autoimmune diseases.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1310796-72-5
- Fòrmula: C25H37F3N4O3
- Peso molecular:498.58
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Descripciòn
IC50 & Target
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CCR2 3 nM (IC50) |
CCR5 5.3 nM (IC50) |
Chemical Information
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No. CAS 1310796-72-5
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Peso molecular 498.58
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Fòrmula C25H37F3N4O3
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SMILES
O=C(N1CCN(C2=CC(C(F)(F)F)=CC=N2)CC1)[C@@]3(C[C@@H](CC3)N[C@@H]4[C@@H](COCC4)OC)C(C)C
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Synonyms
INCB10820
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)