PGN-9856
Based on 1 Customer Validation
PGN-9856 is a selective and high affinity (pKi ≥ 8.3) ligand at EP2 receptor. PGN-9856 is a potetn and non-prostanoid EP2 receptor agonist (pEC50 ≥ 8.5). PGN-9856 shows anti-inflammatory and anti-glaucoma activities.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 98.90%
- No. CAS: 863704-91-0
- Fòrmula: C21H15F2NO4
- Peso molecular:383.34
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Descripciòn
IC50 & Target
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EP2 ≥ 8.5 (pEC50) |
EP2 ≥ 8.3 (pKi) |
Chemical Information
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No. CAS 863704-91-0
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Appearance Solid
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Peso molecular 383.34
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Fòrmula C21H15F2NO4
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Color White to off-white
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SMILES
O=C(O)COC1=CC=CC(NC(C2=CC(C3=CC=CC(F)=C3)=CC=C2F)=O)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
DMSO : 125 mg/mL (326.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6087 mL | 13.0433 mL | 26.0865 mL | 65.2163 mL |
| 5 mM | 0.5217 mL | 2.6087 mL | 5.2173 mL | 13.0433 mL | |
| 10 mM | 0.2609 mL | 1.3043 mL | 2.6087 mL | 6.5216 mL | |
| 15 mM | 0.1739 mL | 0.8696 mL | 1.7391 mL | 4.3478 mL | |
| 20 mM | 0.1304 mL | 0.6522 mL | 1.3043 mL | 3.2608 mL | |
| 25 mM | 0.1043 mL | 0.5217 mL | 1.0435 mL | 2.6087 mL | |
| 30 mM | 0.0870 mL | 0.4348 mL | 0.8696 mL | 2.1739 mL | |
| 40 mM | 0.0652 mL | 0.3261 mL | 0.6522 mL | 1.6304 mL | |
| 50 mM | 0.0522 mL | 0.2609 mL | 0.5217 mL | 1.3043 mL | |
| 60 mM | 0.0435 mL | 0.2174 mL | 0.4348 mL | 1.0869 mL | |
| 80 mM | 0.0326 mL | 0.1630 mL | 0.3261 mL | 0.8152 mL | |
| 100 mM | 0.0261 mL | 0.1304 mL | 0.2609 mL | 0.6522 mL |
PGN-9856 Related Classifications
HY-115462 Related Classifications
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