Pip6a
Pip6a is an arginine-rich cell-penetrating peptide. Pip6a has the ability to deliver associated cargoes across the plasma and endosomal membranes and is stable to serum proteolysis. Pip6a is composed of a hydrophobic core region flanked on each side by arginine-rich domains containing β-alanine and aminohexanoyl spacers. Pip6a-conjugated morpholino phosphorodiamidate oligomer (PMO) dramatically enhanced antisense oligonucleotide (ASO) delivery into striated muscles of myotonic dystrophy (DM1) mice.
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- Fòrmula: C130H231N53O26
- Peso molecular:2952.56
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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Peso molecular 2952.56
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Fòrmula C130H231N53O26
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Sequence
Ac-Arg-{Ahx}-Arg-Arg-{b-Ala}-Arg-Arg-{Ahx}-Arg-Tyr-Gln-Phe-Leu-Ile-Arg-{Ahx}-Arg-{b-Ala}-Arg-{Ahx}-Arg-{b-Ala}
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Sequence Shortening
Ac-R-{Ahx}-RR-{b-Ala}-RR-{Ahx}-RYQFLIR-{Ahx}-R-{b-Ala}-R-{Ahx}-R-{b-Ala}
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pip6a Related Classifications
HY-P10567 Related Classifications
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