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United States

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Referencia número: HY-19198

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SB-201993

SB-201993 is a selective leukotriene B₄ (LTB4) receptor antagonist with a K_i=7.6 nM for LTB4 receptors on human inflammatory cells. SB-201993 inhibits calcium mobilization in inflammatory cells and 5-lipoxygenase activity, exerting anti-inflammatory effects. SB-201993 is promising for research of inflammatory diseases (e.g., dermatitis, arthritis).

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No. CAS: 150399-22-7
Fòrmula: C₃₂H₃₇NO₆S
Peso molecular:563.70

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

SB-201993 Chemical Structure

No. CAS: 150399-22-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- IC₅₀ & Target
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
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Actividad biológica

Descripciòn

IC₅₀ & Target

LTB₄

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Chemical Information

No. CAS 150399-22-7
Peso molecular 563.70
Fòrmula C₃₂H₃₇NO₆S
SMILES

O=C(O)C1=CC=CC(CSCC2=NC(/C=C/C(O)=O)=C(OCCCCCCCCC3=CC=C(OC)C=C3)C=C2)=C1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Sarau HM, et al. In vitro and in vivo pharmacological characterization of SB 201993, an eicosanoid-like LTB4 receptor antagonist with anti-inflammatory activity. Prostaglandins Leukot Essent Fatty Acids. 1999 Jul;61(1):55-64. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Calculadora de dilución

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Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
Pureza y Documentación
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SB-201993

Ver todos los productos específicos de isoformas Leukotriene Receptor