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United States

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Referencia número: HY-161262

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SB03178

SB03178 is a fibroblast activation protein-alpha (FAP) inhibitor. SB03178 can be conjugated with DOTA and can be used for cancer research.

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 2952588-12-2
Fòrmula: C₄₄H₅₆F₂N₁₀O₁₀
Peso molecular:922.97

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

SB03178 Chemical Structure

No. CAS: 2952588-12-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

SB03178 is a fibroblast activation protein-alpha (FAP) inhibitor. SB03178 can be conjugated with DOTA and can be used for cancer research^[1].

Chemical Information

No. CAS 2952588-12-2
Peso molecular 922.97
Fòrmula C₄₄H₅₆F₂N₁₀O₁₀
SMILES

OC(CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(N2CCN(CCCOC3=CC4=C(C(NCC(N5[C@H](C#N)CC(F)(F)C5)=O)=O)C=CN=C4C6=C3C=CC=C6)CC2)=O)CC1)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Bendre S, et al. Development, preclinical evaluation and preliminary dosimetry profiling of SB03178, a first-of-its-kind benzo[h]quinoline-based fibroblast activation protein-α-targeted radiotheranostic for cancer imaging and therapy. Eur J Med Chem. 2024 Feb 13;268:116238. [Content Brief]

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Calculadora de molaridad

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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