SH-E4A-66
SH-E4A-66 is a C2-COUPLr (COvalent Protein Ligator) with carbazole scaffold barring heterogeneous cysteine reactive warheads (acrylamide and chloroacetamide). SH-E4A-66 is capable of coupling with EML4-ALK (EC50=1.5 μM) and inhibiting the activity of EML4-ALK kinase (IC50=2.3 μM).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Fòrmula: C24H18ClN3O3
- Peso molecular:431.87
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
IC50: 2.3 μM (EML4-ALK)[1].
Chemical Information
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Peso molecular 431.87
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Fòrmula C24H18ClN3O3
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SMILES
O=C(N1C(C=CC=C2)=C2C3=C1C=CC=C3)C4=CC(NC(C=C)=O)=CC(NC(CCl)=O)=C4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)