Ternatin
Ternatin (compound 2) is a cyclic heptapeptides that can be isolated from mushroom Coliorus versicolor. Ternatin inhibits fat-accumulation with an IC50 of 0.027 μM in 3T3-L1 adipocytes.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 148619-41-4
- Fòrmula: C37H67N7O8
- Peso molecular:737.97
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| 3T3-L1 | IC50 |
0.027 μM
Compound: 1
|
Inhibition of fat accumulation in mouse 3T3L1 cells assessed as liberated triglyceride after 7 days
Inhibition of fat accumulation in mouse 3T3L1 cells assessed as liberated triglyceride after 7 days
|
[PMID: 18798610] |
| 3T3-L1 | IC50 |
0.027 μM
Compound: 1
|
Inhibition of fat accumulation in mouse 3T3L1 cells after 7 days
Inhibition of fat accumulation in mouse 3T3L1 cells after 7 days
|
[PMID: 19022665] |
| 3T3-L1 | IC50 |
0.027 μM
Compound: 2, cyclo-[D-allo-Ile1-NMe-L-Ala2-NMe-L-Leu3-L-Leu4-NMe-L-Ala5-NMe-D-Ala6-beta-OH-D-Leu7]
|
Inhibition of fat-accumulation in mouse 3T3L1 cells
Inhibition of fat-accumulation in mouse 3T3L1 cells
|
[PMID: 19097891] |
| 3T3-L1 | IC50 |
0.28 μM
Compound: 1
|
Toxicity in mouse 3T3L1 cells
Toxicity in mouse 3T3L1 cells
|
[PMID: 18798610] |
| 3T3-L1 | IC50 |
0.28 μM
Compound: 1
|
Cytotoxicity against mouse 3T3L1 cells
Cytotoxicity against mouse 3T3L1 cells
|
[PMID: 19022665] |
| 3T3-L1 | IC50 |
0.28 μM
Compound: 2, cyclo-[D-allo-Ile1-NMe-L-Ala2-NMe-L-Leu3-L-Leu4-NMe-L-Ala5-NMe-D-Ala6-beta-OH-D-Leu7]
|
Cytotoxicity against mouse 3T3L1 cells
Cytotoxicity against mouse 3T3L1 cells
|
[PMID: 19097891] |
Chemical Information
-
No. CAS 148619-41-4
-
Peso molecular 737.97
-
Fòrmula C37H67N7O8
-
Sequence
Cyclo({Ala(N-Me)}-{d-Ala((N-Me)}-{d-Leu((3R)-3-hydroxy)}-{d-Ile}-{Ala(N-Me)}-Leu-Leu)
-
Sequence Shortening
Cyclo({Ala(N-Me)}-{d-Ala((N-Me)}-{d-Leu((3R)-3-hydroxy)}-{d-Ile}-{Ala(N-Me)}-Leu-Leu)
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)