Tetraasterane
Tetraasterane is a hydrophobic tag that promotes the degradation of ALK protein. Tetraasterane can be used for synthesis of ALK degrader 3 (HY-182087).
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- No. CAS: 259-77-8
- Fòrmula: C12H16
- Peso molecular:160.26
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
Tetraasterane (7 days) conjugated with ALK degrader 3 potently inhibits the proliferation of H3122 cells, with an IC50 of 97.77 nM[1].
Tetraasterane (0.05-2 μM; 24 h) conjugated with ALK degrader 3 induces concentration-dependent degradation of ALK protein in H3122 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 259-77-8
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Peso molecular 160.26
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Fòrmula C12H16
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SMILES
C12C(CC3C4C2)C5C1CC4C3C5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)