TMP778 (Standard)
TMP778 (Standard) is the analytical standard of TMP778 (HY-102075A). This product is intended for research and analytical applications. TMP778 is a potent and selevtive RORγt inverse agonist, with an IC50 of 7 nM in FRET assay.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 1422053-04-0
- Fòrmula: C31H30N2O4
- Peso molecular:494.58
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureza y Documentación
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Help & FAQs
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HY-14422
SR1078RORα/RORγ Agonist -
HY-13421
SR1001RORα/γt Inverse Agonist -
HY-14413
SR3335RORα Inverse Agonist -
HY-101454
SR0987RORγt Agonist -
HY-104037
CintirorgonRORγ Agonist -
HY-112706
PF-06747711RORγt Inverse Agonist -
HY-102075A
TMP778RORγt Inverse Agonist -
HY-19770
GSK2981278RORγ Inverse Agonist -
HY-119366
S18-000003RORγt Inhibitor -
HY-13421R
SR1001 (Standard)RORα/γt Inverse Agonist -
HY-12776
GSK805RORγt Inhibitor -
HY-104037R
Cintirorgon (Standard)Reference Standard
Product Information
Information
Aplicación
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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No. CAS 1422053-04-0
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Peso molecular 494.58
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Fòrmula C31H30N2O4
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SMILES
CC1=NOC(C)=C1[C@@H](C2=CC3=CC(CC(N[C@H](C4=CC=C(C)C=C4C)C5=CC=CC=C5)=O)=CC=C3O2)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Skepner J, et al. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo. J Immunol. 2014 Mar 15;192(6):2564-75. [Content Brief]
[2]. Xiao S, et al. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. Immunity. 2014 Apr 17;40(4):477-89. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TMP778 (Standard) Related Classifications
HY-102075AR Related Classifications
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