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Referencia número: HY-187348

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TT-03597

TT-03597 is a modified NAMPT inhibitor core derived from OT-82 (HY-136241), which serves as a target protein ligand for PROTACs targeting NAMPT. TT-03597 can be used for the synthesis of PROTAC NAMPT Degrader-31 (HY-187347).

Para uso exclusivo en investigación. No vendemos a pacientes.

No. CAS: 1800487-38-0
Fòrmula: C₂₅H₂₆FN₅O
Peso molecular:431.51

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

TT-03597 Chemical Structure

No. CAS: 1800487-38-0

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Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
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Actividad biológica

Descripciòn

In Vitro

TT-03597 serves as the target protein ligand for PROTAC NAMPT Degrader-31 (HY-187347)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 1800487-38-0
Peso molecular 431.51
Fòrmula C₂₅H₂₆FN₅O
SMILES

O=C(NCCCC1=CNN=C1)C(C=C2C#CC3=CC=C(C=C3)F)=CC=C2N4CCNCC4
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Song Y, et al. Discovery of a Potent NAMPT-Targeting PROTAC for the Suppression of Triple-Negative Breast Cancer via Macrophage Reprogramming. Journal of medicinal chemistry. 2026 Jul 23;69(14):16801-16818. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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