UNC8969
UNC8969 (compound 43) is a MERTK/AXL dual inhibitor with IC50s of 1.1±0.8 nM for MERTK and 5.3 ± 2.7 nM for AXL. UNC8969 also exerts a T1/2 of 7.3 h with 5 mg/kg i.v. in mice.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 3036049-17-6
- Fòrmula: C29H41N7O3
- Peso molecular:535.68
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
UNC8969 (0-1000 nM, 2 h) inhibits pMERTK and pAXL dose dependently in NSCLC cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 3036049-17-6
-
Peso molecular 535.68
-
Fòrmula C29H41N7O3
-
SMILES
O=C(C1=C2NC3=CC=C(C(OC/C=C\CNC(N=C1)=N2)=C3)C)N[C@@H]4CC[C@H](CC4)C(NCCN(CC)CC)=O
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UNC8969 Related Classifications
HY-162406 Related Classifications
Powered by Bioz