UVI 3003 (Standard)
UVI 3003 (Standard) is the analytical standard of UVI 3003 (HY-107500). This product is intended for research and analytical applications. UVI 3003 is a highly selective antagonist of retinoid X receptor (RXR), and inhibits xenopus and human RXRα in Cos7 cells, with IC50s of 0.22 and 0.24 μM, respectively.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 847239-17-2
- Fòrmula: C28H36O4
- Peso molecular:436.58
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
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HY-107500
UVI 3003RXR Inhibitor -
HY-14171
BexaroteneRXR Agonist -
HY-108521
HX531RXR Antagonist -
HY-B0091
AdapaleneRAR Agonist -
HY-15682
TTNPBApoptosis Inducer -
HY-14649
Retinoic acidRAR Agonist -
HY-14652
TamibaroteneApoptosis Inducer -
HY-14799
PalovaroteneRARγ Agonist -
HY-15388
TazaroteneRAR Agonist -
HY-14649R
Retinoic acid (Standard) -
HY-14649G
Retinoic acid (GMP)RAR Agonist -
HY-15373
FenretinideAutophagy Inducer
Actividad biológica
Descripciòn
IC50 & Target
IC50: 0.22 μM (Xenopus RXRα, in Cos7 cells), 0.24 μM (Human RXRα, in Cos7 cells)[1]
Chemical Information
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No. CAS 847239-17-2
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Peso molecular 436.58
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Fòrmula C28H36O4
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SMILES
CCCCCOC1=C(C2=CC(/C=C/C(O)=O)=CC=C2O)C=C3C(C(C)(CCC3(C)C)C)=C1
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Zhu J, et al. The unexpected teratogenicity of RXR antagonist UVI3003 via activation of PPARγ in Xenopus tropicalis. Toxicol Appl Pharmacol. 2017 Jan 1;314:91-97. [Content Brief]
[2]. Hebert SL, et al. Effects of retinoic acid signaling on extraocular muscle myogenic precursor cells in vitro. Exp Cell Res. 2017 Dec 1;361(1):101-111. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
UVI 3003 (Standard) Related Classifications
HY-107500R Related Classifications
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