Verbascose
Based on 1 Customer Validation
Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza : 95.0%
- No. CAS: 546-62-3
- Fòrmula: C30H52O26
- Peso molecular:828.72
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
Descripciòn
In Vitro
Verbascose (25, 50, 100, 200, 400 μg/mL; 12, 24, 36, 48 hours) significantly increases the viability of RAW264.7 cells[1].
Verbascose has notable activity of promoting peritoneal macrophages to devour neutral red in a dose-dependent manner and exhibits its maximum activity of cell phagocytosis at a concentration of 200 μg/mL[1].
Verbascose induces significant increases of NO production. Verbascose can enhance the ability of devouring neutral red of peritoneal macrophages and promote the release of nitric oxide and immune reactive molecules such as interleukin (IL)-6, IL-1β, interferon (IFN)-α, and IFN-γ[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 546-62-3
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Appearance Solid
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Peso molecular 828.72
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Fòrmula C30H52O26
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Color White to off-white
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SMILES
OC[C@@H](O1)[C@@H](O)[C@H](O)[C@]1(CO)O[C@@H](O2)[C@H](O)[C@@H](O)[C@H](O)[C@H]2CO[C@@H](O3)[C@H](O)[C@@H](O)[C@@H](O)[C@H]3CO[C@@H](O4)[C@H](O)[C@@H](O)[C@@H](O)[C@H]4CO[C@@H](O5)[C@H](O)[C@@H](O)[C@@H](O)[C@H]5CO
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
In Vitro:
H2O : 100 mg/mL (120.67 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.2067 mL | 6.0334 mL | 12.0668 mL | 30.1670 mL |
| 5 mM | 0.2413 mL | 1.2067 mL | 2.4134 mL | 6.0334 mL | |
| 10 mM | 0.1207 mL | 0.6033 mL | 1.2067 mL | 3.0167 mL | |
| 15 mM | 0.0804 mL | 0.4022 mL | 0.8045 mL | 2.0111 mL | |
| 20 mM | 0.0603 mL | 0.3017 mL | 0.6033 mL | 1.5084 mL | |
| 25 mM | 0.0483 mL | 0.2413 mL | 0.4827 mL | 1.2067 mL | |
| 30 mM | 0.0402 mL | 0.2011 mL | 0.4022 mL | 1.0056 mL | |
| 40 mM | 0.0302 mL | 0.1508 mL | 0.3017 mL | 0.7542 mL | |
| 50 mM | 0.0241 mL | 0.1207 mL | 0.2413 mL | 0.6033 mL | |
| 60 mM | 0.0201 mL | 0.1006 mL | 0.2011 mL | 0.5028 mL | |
| 80 mM | 0.0151 mL | 0.0754 mL | 0.1508 mL | 0.3771 mL | |
| 100 mM | 0.0121 mL | 0.0603 mL | 0.1207 mL | 0.3017 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.