WS-11
WS-11 is a non-covalent reversible BTK inhibitor with IC50s of 3.9 nM and 2.2 nM for wild type, C481S mutation BTK, respectively. WS-11 can form strong π-π interaction with PHE540 and form p-π interaction with LYS430 within the active pocket, besides the strong hydrogen bonds.
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- No. CAS: 2759280-09-4
- Fòrmula: C26H22FN9O2
- Peso molecular:511.51
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 2759280-09-4
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Peso molecular 511.51
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Fòrmula C26H22FN9O2
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SMILES
NC1=C2C(C3=CC=C(C=C3F)C(NC4=NC=CC=C4)=O)=NN(C2=NC=N1)C5CCCN(C5)C6=NC(C=C6)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
WS-11 Related Classifications
HY-169228 Related Classifications
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