MPHOSPH6 - M-phase phosphoprotein 6 Gene

Also Known as MPP; MPP6; MPP-6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10200

Summary

Predicted to enable RNA binding activity. Involved in maturation of 5.8S rRNA. Located in nuclear exosome (RNase complex) and nucleolus. [provided by Alliance of Genome Resources, Jun 2026]
Ubiquitous expression in appendix (RPKM 8.9), urinary bladder (RPKM 8.6) and 24 other tissues.

MPHOSPH6 Products (1)

mRNA Protein Name
NM_005792.2 NP_005783.2 M-phase phosphoprotein 6

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
11719186 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in maturation of 5.8S rRNA IMP
IMP: Inferred from mutant phenotype
17412707 GOA
Cellular Component GO Annotation Evidence Verweise Source
part of exosome (RNase complex) IDA
IDA: Inferred from direct assay
11719186 GOA
part of nuclear exosome (RNase complex) IDA
IDA: Inferred from direct assay
26166824 GOA
located in nucleus IDA
IDA: Inferred from direct assay
8885239 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MPHOSPH6 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
MPHOSPH6 Q99547 EXOSC2 Homo sapiens Q13868
Anti Tag CoIP
33961781
Intra
MPHOSPH6 Q99547 MTREX Homo sapiens P42285
Y2H
15231747
Intra
MPHOSPH6 Q99547 MTREX Homo sapiens P42285
Anti Tag CoIP
33961781
Intra
MPHOSPH6 Q99547 EXOSC10 Homo sapiens Q01780
Y2H
15231747
Intra
MPHOSPH6 Q99547 EXOSC10 Homo sapiens Q01780
Anti Tag CoIP
33961781
Intra
MPHOSPH6 Q99547 EXOSC10 Homo sapiens Q01780
Anti Bait CoIP
17412707
Intra
MPHOSPH6 Q99547 EXOSC10 Homo sapiens Q01780
Pull Down
17412707
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS08612 MPHOSPH8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08613 MPHOSPH9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown