USPL1 - ubiquitin specific peptidase like 1 Gene

Homo sapiens

Also known as C13orf22; D13S106E; bA121O19.1

Gene ID: 10208 | Gene type: protein coding

About USPL1

Cytogenetic location: 13q12.3 Genomic coordinates (GRCh38): 13:30,617,920-30,660,766 (from NCBI)

This gene has 3 transcripts (splice variants) and 205 orthologues. Ubiquitous expression in testis (RPKM 10.5), bone marrow (RPKM 8.9) and 25 other tissues.

Summary

Enables SUMO binding activity and SUMO-specific isopeptidase activity. Involved in several processes, including Cajal body organization; protein desumoylation; and snRNA transcription. Located in Cajal body. [provided by Alliance of Genome Resources, Apr 2022]

USPL1 Products(4)

mRNA	Protein	Name
NM_001321532.2	NP_001308461.1	SUMO-specific isopeptidase USPL1 isoform 2
NM_001321533.2	NP_001308462.1	SUMO-specific isopeptidase USPL1 isoform 3
NM_001321534.2	NP_001308463.1	SUMO-specific isopeptidase USPL1 isoform 3
NM_005800.5	NP_005791.3	SUMO-specific isopeptidase USPL1 isoform 1

USPL1 Protein Structure

Peptidase_C98

DUF4650

0
200
400
600
800
1000
1092 a.a.

Protein Preferred Names

Protein Names

SUMO-specific isopeptidase USPL1

USP-like 1

Related Diseases

Diseases

Alias

Chronic Follicular Conjunctivitis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15572	USPL1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	USPL1	MGD	MGI:2442342
Bos taurus	USPL1	VGNC	VGNC:36740
Canis familiaris	USPL1	VGNC	VGNC:48206
Macaca mulatta	USPL1	VGNC	VGNC:79240
Felis catus	USPL1	VGNC	VGNC:66899
Rattus norvegicus	USPL1	RGD	RGD:1310835

Name
Email *

	Sorry, but the email address you supplied was invalid.