Clk3 - CDC-like kinase 3 Gene

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 102414

Summary

Enables protein serine/threonine kinase activity and protein tyrosine kinase activity. Involved in protein phosphorylation. Acts upstream of or within peptidyl-tyrosine phosphorylation and protein autophosphorylation. Located in nucleus. Is expressed in several structures, including cerebral cortex; craniocervical region bone; ganglia; neural retina; and thyroid gland. Orthologous to human CLK3 (CDC like kinase 3). [provided by Alliance of Genome Resources, Apr 2022]

Clk3 Products (8)

mRNA Protein Name
NM_001410176.1 NP_001397105.1 dual specificity protein kinase CLK3 isoform 1
NM_001410177.1 NP_001397106.1 dual specificity protein kinase CLK3 isoform 1
NM_001410178.1 NP_001397107.1 dual specificity protein kinase CLK3 isoform 1
NM_001410179.1 NP_001397108.1 dual specificity protein kinase CLK3 isoform 1
NM_001410180.1 NP_001397109.1 dual specificity protein kinase CLK3 isoform 1
NM_001410181.1 NP_001397110.1 dual specificity protein kinase CLK3 isoform 2
NM_001410182.1 NP_001397111.1 dual specificity protein kinase CLK3 isoform 2
NM_007713.5 NP_031739.4 dual specificity protein kinase CLK3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
9307018 MGI
enables protein tyrosine kinase activity IDA
IDA: Inferred from direct assay
9307018 MGI
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within peptidyl-tyrosine phosphorylation IDA
IDA: Inferred from direct assay
9307018 MGI
acts upstream of or within protein autophosphorylation IDA
IDA: Inferred from direct assay
9307018 MGI
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
9307018 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in nucleus IDA
IDA: Inferred from direct assay
9307018 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dual specificity protein kinase CLK3

  • cdc2/CDC28-like protein kinase 3

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
製品番号 製品名 製品効果
純度 Phase
HY-137443 Ipivivint Inhibitor 99.95% Phase 1

Pre-clinical Phase

Bioactive Molecules (12)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-115470 CLK-IN-T3 Inhibitor 99.78% Unkown
HY-112296 T025 99.64% Unkown
HY-15951 ML167 Inhibitor 98.62% Unkown
HY-12828 KH-CB19 Inhibitor 99.31% Unkown
HY-103647 K00546 Inhibitor 99.48% Unkown
HY-155723 Leucettinib-92 Inhibitor 98.54% Unkown
HY-12828A KH-CB20 Inhibitor 99.80% Unkown
HY-E70692 CLK3 Recombinant Human Active Protein Kinase / Unkown
HY-RS02818 CLK3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-159963 PfCLK3-IN-1 Inhibitor / Unkown
HY-RS16964 Clk3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23407 Clk3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Clk3 NCBI NCBI:1198