RCBTB2 - RCC1 and BTB domain containing protein 2 Gene

Also Known as RLG; CHC1L

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 1102

Summary

This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a Guanine Nucleotide exchange factor. This gene is observed to be lost or underexpressed in prostate cancers. There is a pseudogene of this gene on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Ubiquitous expression in thyroid (RPKM 11.8), ovary (RPKM 6.4) and 24 other tissues.

RCBTB2 Products (12)

mRNA Protein Name
NM_001268.4 NP_001259.1 RCC1 and BTB domain-containing protein 2 isoform 2
NM_001286830.2 NP_001273759.1 RCC1 and BTB domain-containing protein 2 isoform 1
NM_001286831.2 NP_001273760.1 RCC1 and BTB domain-containing protein 2 isoform 3
NM_001286832.2 NP_001273761.1 RCC1 and BTB domain-containing protein 2 isoform 4
NM_001352424.2 NP_001339353.1 RCC1 and BTB domain-containing protein 2 isoform 2
NM_001352425.2 NP_001339354.1 RCC1 and BTB domain-containing protein 2 isoform 2
NM_001352426.2 NP_001339355.1 RCC1 and BTB domain-containing protein 2 isoform 3
NM_001352427.2 NP_001339356.1 RCC1 and BTB domain-containing protein 2 isoform 4
NM_001352428.2 NP_001339357.1 RCC1 and BTB domain-containing protein 2 isoform 4
NM_001352429.2 NP_001339358.1 RCC1 and BTB domain-containing protein 2 isoform 5 precursor
NM_001352430.2 NP_001339359.1 RCC1 and BTB domain-containing protein 2 isoform 6
NM_001352431.2 NP_001339360.1 RCC1 and BTB domain-containing protein 2 isoform 7

RCBTB2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RCBTB2 O95199 UBE2I Homo sapiens Q7KZS0
Y2H Prey Pooling
25416956
Intra
RCBTB2 O95199 MORF4L1 Homo sapiens Q9UBU8-2
Validated Y2H
32296183
Intra
RCBTB2 O95199 NUDCD2 Homo sapiens Q8WVJ2
Lumier
25036637
Intra
RCBTB2 O95199 NUDCD2 Homo sapiens Q8WVJ2
Anti Tag CoIP
33961781
Intra
RCBTB2 O95199 FARS2 Homo sapiens O95363
Validated Y2H
32296183
Intra
RCBTB2 O95199 FARS2 Homo sapiens O95363
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11782 RCBTB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown