DDX42 - DEAD-box helicase 42 Gene
Also Known as RHELP; RNAHP; SF3B8; DDX42P; SF3b125
Species: Homo sapiens
About DDX42
This gene has 18 transcripts (splice variants), 211 orthologues and 38 paralogues. Ubiquitous expression in testis (RPKM 27.4), ovary (RPKM 25.5) and 25 other tissues.
Summary
This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]
DDX42 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_007372.3 | NP_031398.2 | ATP-dependent RNA helicase DDX42 |
| NM_203499.3 | NP_987095.1 | ATP-dependent RNA helicase DDX42 |
DDX42 Protein Structure
DEAD: DEAD/DEAH box helicase (277 - 448)
Helicase_C: Helicase conserved C-terminal domain (517 - 593)
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- 200
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- 938 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ATP-dependent RNA helicase DDX42 |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Canis familiaris | DDX42 | VGNC | VGNC:39858 |
| Felis catus | DDX42 | VGNC | VGNC:61409 |
| Bos taurus | DDX42 | VGNC | VGNC:27968 |
| Macaca mulatta | DDX42 | VGNC | VGNC:71661 |
| Mus musculus | DDX42 | MGD | MGI:1919297 |
| Rattus norvegicus | DDX42 | RGD | RGD:1304909 |
| Others | DDX42 | NCBI |