2. Gene
  3. ARHGAP33 - Rho GTPase activating protein 33 Gene

ARHGAP33 - Rho GTPase activating protein 33 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as SNX26; TCGAP; NOMA-GAP

Gene ID: 115703 | Gene type: protein coding

About ARHGAP33

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:35,775,564-35,788,822 (from NCBI)

This gene has 12 transcripts (splice variants), 112 orthologues and 3 paralogues. Broad expression in testis (RPKM 7.3), brain (RPKM 5.7) and 23 other tissues.

Summary

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Alternative splice variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]

ARHGAP33 Products(3)

mRNA Protein Name
NM_001172630.2 NP_001166101.1 rho GTPase-activating protein 33 isoform 2
NM_001366178.1 NP_001353107.1 rho GTPase-activating protein 33 isoform 3
NM_052948.4 NP_443180.2 rho GTPase-activating protein 33 isoform 1

ARHGAP33 Protein Structure

SH3_9

SH3_9: Variant SH3 domain (193 - 244)

RhoGAP

RhoGAP: RhoGAP domain (329 - 475)

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  • 1126 a.a.
Protein Preferred Names Protein Names

rho GTPase-activating protein 33

neurite outgrowth multiadaptor RhoGAP protein

Related Diseases

Diseases Alias
Noma

Cancrum Oris

Gangrenous Stomatitis

Oro-Facial Gangrene

Noma Neonatorum

Oral Gangrene

Oro-Facial Noma

Stomatitis Gangrenosa

Stomatonecrosis

Gangrene Stomatitis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00932 ARHGAP33 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ARHGAP33 RGD RGD:2318374
Bos taurus ARHGAP33 VGNC VGNC:26091
Macaca mulatta ARHGAP33 VGNC VGNC:69887
Mus musculus ARHGAP33 MGD MGI:2673998
Canis familiaris ARHGAP33 VGNC VGNC:84858
Felis catus ARHGAP33 VGNC VGNC:59890