WDFY2 - WD repeat and FYVE domain containing 2 Gene

Also Known as PROF; WDF2; ZFYVE22

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 115825

About WDFY2

Cytogenetic location: 13q14.3 Genomic coordinates (GRCh38): 13:51,584,462-51,767,709 (from NCBI)

This gene has 3 transcripts (splice variants), 220 orthologues and 10 paralogues. Ubiquitous expression in skin (RPKM 5.8), bone marrow (RPKM 4.0) and 25 other tissues.

Summary

This gene encodes a protein that contains two WD domains and an FYVE zinc finger region. The function of this gene is unknown. An alternatively spliced transcript variant of this gene may exist. [provided by RefSeq, Jul 2008]

WDFY2 Products (1)

mRNA Protein Name
NM_052950.4 NP_443182.1 WD repeat and FYVE domain-containing protein 2

WDFY2 Protein Structure

WD40

WD40: WD domain, G-beta repeat (190 - 227)

WD40

WD40: WD domain, G-beta repeat (237 - 270)

FYVE

FYVE: FYVE zinc finger (284 - 351)

WD40

WD40: WD domain, G-beta repeat (358 - 394)

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Protein Preferred Names Protein Names

WD repeat and FYVE domain-containing protein 2

  • WD40 and FYVE domain containing 2

WDFY2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
WDFY2 Q96P53 RPRM Homo sapiens Q9NS64
Y2H Array
32296183
Intra
WDFY2 Q96P53 RPRM Homo sapiens Q9NS64
Y2H Prey Pooling
32296183
Intra
WDFY2 Q96P53 RPRM Homo sapiens Q9NS64
Validated Y2H
32296183
Intra
WDFY2 Q96P53 YIF1A Homo sapiens O95070
Y2H Array
32296183
Intra
WDFY2 Q96P53 YIF1A Homo sapiens O95070
Y2H Prey Pooling
32296183
Intra
WDFY2 Q96P53 NUDC Homo sapiens Q9Y266
Anti Tag CoIP
33961781
Intra
WDFY2 Q96P53 NUDC Homo sapiens Q9Y266
Lumier
25036637
Intra
WDFY2 Q96P53 ARL6IP1 Homo sapiens Q15041
Y2H Array
32296183
Intra
WDFY2 Q96P53 ARL6IP1 Homo sapiens Q15041
Y2H Prey Pooling
32296183
Intra
WDFY2 Q96P53 SYP Homo sapiens P08247
Y2H Prey Pooling
32296183
Intra
WDFY2 Q96P53 SYP Homo sapiens P08247
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Hyperglobulinemic Purpura

  • Purpura, Hyperglobulinemic
Laryngeal Tuberculosis

  • Tuberculosis, Laryngeal
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15755 WDFY2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus WDFY2 RGD RGD:1307337
Felis catus WDFY2 VGNC VGNC:67010
Canis familiaris WDFY2 VGNC VGNC:54388
Mus musculus WDFY2 MGD MGI:2442811
Bos taurus WDFY2 VGNC VGNC:53847
Macaca mulatta WDFY2 VGNC VGNC:97842
Others WDFY2 NCBI