NIBAN1 - niban apoptosis regulator 1 Gene

Also Known as GIG39; NIBAN; C1orf24; FAM129A

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 116496

About NIBAN1

Cytogenetic location: 1q25.3 Genomic coordinates (GRCh38): 1:184,791,032-184,974,508 (from NCBI)

This gene has 5 transcripts (splice variants), 260 orthologues and 2 paralogues. Broad expression in heart (RPKM 58.9), esophagus (RPKM 34.2) and 18 other tissues.

Summary

This gene encodes a member of the family with sequence similarity 129 protein family. This gene is highly expressed in several Cancer cells and may serve as a prognostic marker for certain cancers. The encoded protein may play a role in regulating p53-mediated Apoptosis. [provided by RefSeq, Sep 2016]

NIBAN1 Products (1)

mRNA Protein Name
NM_052966.4 NP_443198.1 protein Niban 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
22510990 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16949643 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein Niban 1

  • cell growth-inhibiting gene 39 protein

NIBAN1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
NIBAN1 Q9BZQ8 AKT1 Homo sapiens P31749
Anti Bait CoIP
22510990
Intra
NIBAN1 Q9BZQ8 FHL2 Homo sapiens Q14192
Y2H Array
32296183
Intra
NIBAN1 Q9BZQ8 FHL2 Homo sapiens Q14192
Y2H Prey Pooling
25416956
Intra
NIBAN1 Q9BZQ8 FHL2 Homo sapiens Q14192
Y2H Prey Pooling
32296183
Intra
NIBAN1 Q9BZQ8 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra
NIBAN1 Q9BZQ8 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra
NIBAN1 Q9BZQ8 NPM1 Homo sapiens P06748
Pull Down
22510990
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Granular Cell Carcinoma

  • Granular Cell Cancer

  • Granular Cell Adenocarcinoma
Childhood Central Nervous System Primitive Neuroectodermal Neoplasm

  • Pediatric Cns Pnet

  • Childhood Central Nervous System Primitive Neuroectodermal Tumor
Thyroid Tumor
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09293 NIBAN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus NIBAN1 VGNC VGNC:63800
Mus musculus NIBAN1 MGD MGI:2137237
Macaca mulatta NIBAN1 VGNC VGNC:75192
Rattus norvegicus NIBAN1 RGD RGD:71088
Canis familiaris NIBAN1 VGNC VGNC:40589
Bos taurus NIBAN1 VGNC VGNC:28726
Others NIBAN1 NCBI