Ppp1r12a - protein phosphatase 1, regulatory subunit 12A Gene

Also Known as M110; MBSP; Mypt1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116670

Summary

Enables phosphoprotein Phosphatase activity. Predicted to be involved in several processes, including centrosome cycle; positive regulation of nitrogen compound metabolic process; and protein dephosphorylation. Predicted to act upstream of or within cellular response to xenobiotic stimulus and regulation of nucleocytoplasmic transport. Predicted to be located in several cellular components, including contractile fiber; cytoskeleton; and kinetochore. Predicted to be part of PTW/PP1 Phosphatase complex. Predicted to be active in A band and Z disc. Orthologous to human PPP1R12A (protein Phosphatase 1 regulatory subunit 12A). [provided by Alliance of Genome Resources, Apr 2022]

Ppp1r12a Products (1)

mRNA Protein Name
NM_053890.2 NP_446342.2 protein phosphatase 1 regulatory subunit 12A

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables phosphoprotein phosphatase activity IDA
IDA: Inferred from direct assay
8543033 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
15545284 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein phosphatase 1 regulatory subunit 12A

  • PP-1M

  • myosin phosphatase, target subunit 1

  • myosin phosphatase-targeting subunit 1

  • protein phosphatase 1, regulatory (inhibitor) subunit 12A

  • protein phosphatase myosin-binding subunit

  • protein phosphatase subunit 1M

  • serine/threonine protein phosphatas

Ppp1r12a Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Ppp1r12a Q10728 NF2 Homo sapiens P35240
Anti Bait CoIP
16885985
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10978 PPP1R12A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppp1r12a NCBI NCBI:4659