RHEBL1 - RHEB like 1 Gene

Also Known as RHEBL1c

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 121268

Summary

Enables GTP binding activity. Involved in TOR signaling. Located in cytoplasm. [provided by Alliance of Genome Resources, Jun 2026]
Low expression observed in reference dataset.

RHEBL1 Products (2)

mRNA Protein Name
NM_001303126.2 NP_001290055.1 GTPase RhebL1 isoform 2
NM_144593.3 NP_653194.1 GTPase RhebL1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables GTP binding IDA
IDA: Inferred from direct assay
12869548 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
24722188 GOA
Biological Process GO Annotation Evidence References Source
involved in TOR signaling IMP
IMP: Inferred from mutant phenotype
12869548 GOA
involved in positive regulation of NF-kappaB transcription factor activity IDA
IDA: Inferred from direct assay
16328882 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
16328882 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RHEBL1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
RHEBL1 Q8TAI7 PRKAB2 Homo sapiens O43741
Y2H Array
25416956
Intra
RHEBL1 Q8TAI7 SPRED1 Homo sapiens Q7Z699
Validated Y2H
32814053
Intra
RHEBL1 Q8TAI7 SPRED1 Homo sapiens Q7Z699
Y2H Pooling
32814053
Intra
RHEBL1 Q8TAI7 SPRED1 Homo sapiens Q7Z699
Y2H Array
32814053
Intra
RHEBL1 Q8TAI7 FHL3 Homo sapiens Q13643
Y2H Prey Pooling
25416956
Intra
RHEBL1 Q8TAI7 FHL3 Homo sapiens Q13643
Y2H Array
25416956
Intra
RHEBL1 Q8TAI7 APPL1 Homo sapiens Q9UKG1
Validated Y2H
25416956
Intra
RHEBL1 Q8TAI7 APPL1 Homo sapiens Q9UKG1
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction