Cmas - cytidine monophospho-N-acetylneuraminic acid synthetase Gene

Also Known as CMPNeu5Ac; D6Bwg0250e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12764

Summary

Predicted to enable N-acylneuraminate cytidylyltransferase activity. Predicted to act upstream of or within CMP-N-acetylneuraminate biosynthetic process. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; liver; nervous system; and sensory organ. Used to study focal segmental glomerulosclerosis. Orthologous to human CMAS (cytidine monophosphate N-acetylneuraminic acid synthetase). [provided by Alliance of Genome Resources, Apr 2022]

Cmas Products (3)

mRNA Protein Name
NM_001409575.1 NP_001396504.1 N-acylneuraminate cytidylyltransferase isoform 2
NM_001409576.1 NP_001396505.1 N-acylneuraminate cytidylyltransferase isoform 3
NM_009908.3 NP_034038.2 N-acylneuraminate cytidylyltransferase isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables N-acylneuraminate cytidylyltransferase activity IDA
IDA: Inferred from direct assay
11893746 MGI
Biological Process GO Annotation Evidence References Source
involved in CMP-N-acetylneuraminate biosynthetic process IMP
IMP: Inferred from mutant phenotype
30382946 MGI
Cellular Component GO Annotation Evidence References Source
is active in nucleoplasm IDA
IDA: Inferred from direct assay
11893746 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

N-acylneuraminate cytidylyltransferase

  • CMP-N-acetylneuraminic acid synthase

  • CMP-N-acetylneuraminic acid synthetase

  • CMP-Neu5Ac synthase

  • CMP-NeuNAc synthase

  • CMP-NeuNAc synthetase

  • CMP-sialic acid synthetase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (17)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1098 Ac2-26 Inhibitor 99.43% Unkown
HY-W013508 I2959 98.28% Unkown
HY-101106 AR7 Antagonist 99.38% Unkown
HY-134923 CA77.1 Inducer 99.92% Unkown
HY-112486 TA-316 99.50% Unkown
HY-112483 QX77 Inducer 99.48% Unkown
HY-155747 FDW028 Inhibitor 99.51% Unkown
HY-P1098A Ac2-26 TFA Inhibitor 98.09% Unkown
HY-P1098B Ac2-26 ammonium Degrader 97.45% Unkown
HY-173150 Hapalindole Q Ligand / Unkown
HY-RS02853 CMA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS02854 CMAS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19313 Cma1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22126 Cmas Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25439 Mas1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25804 Cma1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28648 Cmas Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cmas NCBI NCBI:55907