Ccr8 - chemokine (C-C motif) receptor 8 Gene

Mus musculus

Also known as C-C; CCR-8; CKR-8; mCCR8; Cmkbr8; CC-CKR-8; C-C CKR-8

Gene ID: 12776 | Gene type: protein coding

About Ccr8

Chromosome 9: 119,921,180-119,923,972 forward strand.GRCm39:CM001002.3

This gene has 1 transcript (splice variant), 236 orthologues, 25 paralogues and is associated with 7 phenotypes. Biased expression in thymus adult (RPKM 6.3), mammary gland adult (RPKM 1.1) and 3 other tissues.

Summary

Enables C-C Chemokine Receptor activity. Acts upstream of or within chemotaxis. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Is expressed in central nervous system; retina; and thymus primordium. Orthologous to human CCR8 (C-C motif Chemokine Receptor 8). [provided by Alliance of Genome Resources, Apr 2022]

Ccr8 Products(1)

mRNA	Protein	Name
NM_007720.2	NP_031746.1	C-C chemokine receptor type 8

Ccr8 Protein Structure

7tmA_CCR8

0
100
200
300
353 a.a.

Protein Preferred Names

Protein Names

C-C chemokine receptor type 8

C-C motif chemokine receptor 8

Related Agents

Pre-clinical Phase

Bioactive Molecules (8)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-119217	AZ084	Antagonist	99.69%	Unkown
HY-101038A	ZK756326 dihydrochloride	Agonist	99.88%	Unkown
HY-122219	R243	Antagonist	98.01%	Unkown
HY-121885	LMD-009	Agonist	99.76%	Unkown
HY-144197	CCR8 antagonist 1	Antagonist	98.71%	Unkown
HY-144200	CCR8 antagonist 2	Antagonist	99.71%	Unkown
HY-153669	SB-649701	Antagonist	/	Unkown
HY-160647	CCR8 antagonist 3	Antagonist	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ccr8	NCBI	NCBI:1237
Macaca fascicularis	Ccr8	NCBI	NCBI:102132857
Macaca mulatta	Ccr8	NCBI	NCBI:693806

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