ICA1L - islet cell autoantigen 1 like Gene

Also Known as ALS2CR14; ALS2CR15

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 130026

Summary

Predicted to enable membrane curvature sensor activity. Predicted to be involved in membrane bending and regulation of secretion. Predicted to act upstream of or within spermatid development. Predicted to be located in acrosomal vesicle. Predicted to be active in secretory granule membrane. [provided by Alliance of Genome Resources, Jun 2026]
Broad expression in brain (RPKM 3.9), testis (RPKM 2.5) and 22 other tissues.

ICA1L Products (4)

mRNA Protein Name
NM_001288622.3 NP_001275551.1 islet cell autoantigen 1-like protein isoform 1
NM_001288623.2 NP_001275552.1 islet cell autoantigen 1-like protein isoform 1
NM_001288624.2 NP_001275553.1 islet cell autoantigen 1-like protein isoform 3
NM_138468.7 NP_612477.3 islet cell autoantigen 1-like protein isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ICA1L Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ICA1L Q8NDH6 KIFC3 Homo sapiens Q9BVG8
Y2H Prey Pooling
25416956
Intra
ICA1L Q8NDH6 KIFC3 Homo sapiens Q9BVG8
Validated Y2H
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-183252 ICA-1S / Unkown
HY-RS06511 ICA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17958 Ica1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24429 Ica1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown